Investigator, Lady Davis Institute
Assistant Professor, Department of Medicine, McGill University
Associate member, Department of Epidemiology and Biostatistics, McGill University
Jonathan Afilalo is an assistant professor (tenure track) in the Department of Medicine and associate member in the Department of Epidemiology and Biostatistics at McGill University. Dr. Afilalo is a cardiologist and clinician-scientist in the Divisions of Cardiology and Clinical Epidemiology at the Jewish General Hospital, with cross-appointment at the McGill University Health Center. He completed his residency training in cardiology and MSc degree in epidemiology at McGill University, and then went on to pursue fellowship training in echocardiography and cardiac MRI at Harvard University.
Major Research Activities
Primary research interests include Frailty, Aging biology, Risk prediction before cardiac surgery and TAVI, Cardiac MRI, Echocardiography, and the Right ventricle. Dr. Afilalo is the PI of the international “FRAILTY-AVR” study comparing the impact of frailty assessment tools in elderly patients undergoing transcatheter and surgical aortic valve replacement. The translational arm of this research is dedicated to the discovery and validation of novel biomarkers for frailty. He is the PI of the “POSSE” registry (Pre-Operative Surgical Stratification using Echocardiography), which has yielded insights into the prognostic value of the echocardiogram in cardiac surgery patients. Dr. Afilalo was a co-author on the American Society of Echocardiography guidelines for right heart evaluation.
Recent Publications
Afilalo J, Flynn AW, Shimony A, Rudski LG, Agnihotri AK, Morin JF, Castrillo C, Shahian DM, Picard MH. Incremental value of the preoperative echocardiogram to predict mortality and major morbidity in coronary artery bypass surgery. Circulation. 2013 Jan 22;127(3):356-64.
Flynn AW, Afilalo J, Agnihotri AK, Castrillo C, Shahian DM, Picard MH. Aortic sclerosis is associated with mortality and major morbidity in patients undergoing coronary artery bypass surgery. Heart. 2013 Feb;99(4):247-52.
Afilalo J, Therrien J, Pilote L, Ionescu-Ittu R, Martucci G, Marelli AJ. Geriatric congenital heart disease: Burden of Disease and Predictors of Mortality. In press at J Am Coll Cardiol 2011. Sep 27; 58(14): 1509-1515.