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Stéphane Richard’s laboratory has a long-standing interest in fields of cancer and neuroscience. The research is aimed at understanding the roles of arginine methylation, RNA binding proteins and DNA damage signaling in diseases such as cancer and neurological diseases.
Targeting arginine methylation in cancer (breast, melanoma and leukemia) and defining its substrates.
The specific research areas in the laboratory include:
Srour N, Khan S, Richard S. J Inflamm Res. 2022 May 13;15:2939-2958. doi: 10.2147/JIR.S364190. eCollection 2022.
Srour N, Villarreal OD, Hardikar S, Yu Z, Preston S, Miller WH Jr, Szewczyk MM, Barsyte-Lovejoy D, Xu H, Chen T, Del Rincón SV, Richard S. Cell Rep. 2022 Mar 29;38(13):110582. doi: 10.1016/j.celrep.2022.110582. PMID: 35354055; PMCID: PMC9838175.
Cai T, Cinkornpumin JK, Yu Z, Villarreal OD, Pastor WA, Richard S. Cell Rep. 2021 Jul 13;36(2):109337. doi: 10.1016/j.celrep.2021.109337. PMID: 34260915.
Yu Z, Mersaoui SY, Guitton-Sert L, Coulombe Y, Song J, Masson JY, Richard S. NAR Cancer. 2020 Sep;2(3):zcaa028. doi: 10.1093/narcan/zcaa028. Epub 2020 Sep 25.
Mersaoui SY, Yu Z, Coulombe Y, Karam M, Busatto FF, Masson JY, Richard S. EMBO J. 2019 Aug 1;38(15):e100986. doi: 10.15252/embj.2018100986. Epub 2019 Jun 21.